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How Does Ceftriaxone Injection Work in the Body? (112 views)
17 Apr 2025 12:38
Ceftriaxone injection is a broad-spectrum cephalosporin antibiotic that combats bacterial infections by inhibiting cell wall synthesis. After administration, ceftriaxone injection rapidly distributes throughout the body, penetrating tissues and fluids, including the cerebrospinal fluid. It binds to penicillin-binding proteins on bacterial cell walls, disrupting peptidoglycan synthesis, which weakens the cell wall and leads to bacterial lysis. Effective against gram-positive and gram-negative bacteria, ceftriaxone injection is commonly used for infections like pneumonia, meningitis, and urinary tract infections. Its long half-life allows once-daily dosing. The drug is excreted primarily via the kidneys and bile, ensuring sustained therapeutic levels.
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